FRANKFURT, Germany- (BUSINESS WIRE)-Merz Therapeutics, mutungamiri mumunda weurotoxins uye bhizinesi riri pasi peMerz Group, uye Teijin Pharma Limited, kambani yeTeijin Group's hutano hwehutano, vakazivisa pamwe nhasi kuti Teijin Pharmaceuticals yakunda mvumo kubva kuJapan Ministry of Health, Labor and Welfare (MHLW) kushandisa Xeomin® (incobotulinumtoxinA) mu50, 100 kana 200 mayuniti ejekiseni re intramuscular kuitira kurapwa kwemakumbo ezasi.
Lower limb spasm chiratidzo chepamusoro mota neuron syndrome, iyo inonyanya kuratidzwa nekuwedzera kwemhasuru toni yemakumbo uye kunyanyisa kufara kwekutambanudza reflex se sequelae yesitiroko.Zviratidzo zvikuru kuoma mukufamba zvakajairika uye njodzi yakawedzera yekudonha nekuda kwehunde isina kugadzikana, yakaoma kana yakavharidzirwa mabasa muhupenyu hwezuva nezuva.Kurapa kwakajairika kwemakumbo emakumbo kunosanganisira kudzoreredzwa kwemuviri uye kushandisa zvemuromo zvinozorodza tsandanyama kana neuromuscular blockers, senge botulinum toxin mhando A.
Stefan Brinkmann, CEO weMerz Therapeutics, akati: "Mvumo yakawedzerwa inoratidza chiitiko chakakosha kuMerz Therapeutics uye mhedzisiro yekudyidzana kwedu neTeijin Pharmaceuticals.Isu tinovimba kuti vatinoshanda navo vachabudirira kuunza iyi yakakosha chiratidzo kune vanachiremba veJapan nevarwere. "
Dr. Stefan Albrecht, Mutevedzeri Mukuru weGlobal R&D, Merz Therapeutics: “Uku kuwedzera kwemazita muJapan ndomumwe muenzaniso wakatanhamara wemabhenefiti ayo Xeomin ® inopa kuvarwere vazhinji vane post-stroke spasticity.Vanachiremba zvino vanogona kusarudza kurapa hutsinye hwepazasi uye hwepamusoro, kana kuti vanogona kuchinjika sezvinodiwa Nyorera madosi ega ega nemazvo.Tinodada nebudiriro iyi, kunyanya kubatana kwakanakisa nemumwe wedu Teijin. "
Teijin Pharmaceutical President Ichiro Watanabe akati: "Teijin Pharmaceutical inopa akasiyana siyana emishonga, kusanganisira osteoporosis marapirwo nemidziyo yekurapa, senge ruzha rwekumhanyisa kukurumidza kurapa kwekutyoka kwevarwere vane zvirwere zvemusculoskeletal.Mukupindura kushanduka kwehuwandu hwevanhu uye kuwedzera ruzivo rwehutano, Tiri kutanga mishonga mitsva inoshanda uye mhinduro, kusanganisira kuzadzikiswa kwenharaunda yakagadzikana.Teijin Pharmaceuticals inoenderera mberi nekubatsira kuvandudza hupenyu hwevarwere (QOL) nekupa nzira itsva dzekurapa zvirwere zvine zvinodiwa zvisina kukwana.”
Xeomin® inobata zvinobudirira peripheral cholinergic nerve endings nekuderedza kusimba kwemhasuru dzekuzvidira, uye inobvisa kushushikana kwetsandanyama nekudzivisa kuburitswa kweurotransmitter inonzi acetylcholine.Iyo yakanyanya kucheneswa neurotoxin ndiyo yega inoshandiswa muXeomin®.Inogadzirwa nekubvisa mapuroteni akaoma kubva mumhando yeA botulinum toxin yakagadzirwa neClostridium botulinum uchishandisa teknolojia yekuchenesa yakagadzirwa naMerz Pharma GmbH & Co. KGaA.Kushaikwa kwemapuroteni akaoma kunobvumira Xeomin® kuderedza kugadzirwa kwe neutralizing antibodies inogona kuderedza kushanda.Kuvandudzika kunokosha mu plantar flexor modified ashworth scale (MAS) chikamu chakaonekwa muchikamu chechitatu chekiriniki yekuedza muJapan.
Xeomin® inogoverwa neMerz Pharmaceuticals GmbH munyika dzinopfuura makumi manomwe uye inoshandiswa kurapa varwere vane chepamusoro chemakumbo spasm, cervical dystonia, blepharospasm kana kuwandisa salivation.Teijin Pharmaceuticals yakasaina rezinesi rakasarudzika uye chibvumirano chekusimudzira chakabatana cheXeomin® kuJapan neMerz muna 2017, uye yakatanga kutengesa zvega Xeomin® muna Zvita 2020 mushure mekuwana mvumo kubva kubazi rezvehutano, basa nekugara zvakanaka (MHLW) yekuJapan.Zvichienderana neMerz's Phase III kiriniki yekuyedza muJapan, iyo ichangobva kuwanikwa mvumo yekuwedzera yakashandura dzimwe dzemvumo dzakatenderwa.
Kazhinji, kune vanhu vakuru, Xeomin® inofanirwa kubaiwa mumhasuru dzakawanda dzakaomarara.* Iyo yakanyanya dhigirii pakutonga i400 mayuniti, asi inofanirwa kuderedzwa zvakafanira kusvika padiki dosi zvichienderana nerudzi uye nhamba yeinotangwa tonic tsandanyama.Kana mhedzisiro yedosi yapfuura yadzikira, kudzokorora madosi anobvumidzwa.Nguva yedosing inofanira kuva mavhiki gumi nemaviri kana kupfuura, asi inogona kupfupiswa kusvika kumavhiki gumi zvichienderana nezviratidzo.
* Myotonic: gastrocnemius (medial head, lateral head), soleus, posterior tibialis, flexor digitorum longus, nezvimwewo.
Merz Therapeutics ibhizinesi reMerz Pharmaceuticals GmbH rakazvipira kuvandudza hupenyu hwevarwere pasirese.Nekutsvagisa kwayo kusingaverengeki, kusimudzira uye hunyanzvi tsika, Merz Therapeutics inovavarira kusangana nezvinodiwa nevarwere zvisingaite uye kuwana mhedzisiro iri nani.Merz Therapeutics inotsvaga kuzadzisa izvo zvakasarudzika zvinodiwa zvevanhu vanotambura nekusagadzikana kwekufamba, chirwere chetsinga, chirwere chechiropa, uye mamwe mamiriro ehutano anokanganisa zvakanyanya kunaka kwehupenyu hwevarwere.Merz Therapeutics ine mahofisi makuru muFrankfurt, Germany, ine mahofisi evamiririri munyika dzinopfuura makumi mapfumbamwe, uye bazi rekuNorth America muRaleigh, North Carolina.Merz Pharmaceuticals GmbH chikamu cheMerz Group, kambani yakazvimiririra yemhuri iyo yakazvipira kugadzira hunyanzvi hunozadzisa zvinodiwa nevarwere nevatengi kweanopfuura makore zana negumi.
Teijin (Tokyo Stock Exchange code: 3401) iboka repasi rose rinotungamirirwa neteknolojia rinopa mhinduro dzepamusoro-soro mumunda wekukosha kwezvakatipoteredza;kuchengeteka, kuchengeteka, uye kuderedza njodzi;pamwe nekuchinja kwevanhu uye kuwedzera ruzivo rwehutano.Teijin yakavambwa muna 1918 seyekutanga rayon kugadzira muJapan, uye parizvino yakagadzira bhizinesi rakasiyana-siyana rinofukidza nzvimbo nhatu dzemabhizinesi makuru: zvemhando yepamusoro zvinosanganisira aramid, carbon fiber uye composite zvinhu, pamwe neresin nepurasitiki kugadzira, Firimu. , polyester fiber uye kugadzira chigadzirwa;kurapwa, kusanganisira mishonga uye midziyo yehutano yemumba yemapfupa / majoini, kufema system, uye chirwere chemoyo / metabolic, mukoti uye pre-symptomatic care;uye IT, kusanganisira yezvokurapa, yemakambani uye B2B mhinduro dzeruzhinji masisitimu, pamwe nesoftware yakaputirwa uye B2C online masevhisi ekuvaraidza kwedhijitari.Sezvinoratidzwa muchiratidzo che "Human Chemistry, Human Solutions", Teijin yakazvipira zvakanyanya kune vanobatana nayo uye inotarisira kuve kambani inotsigira nzanga yeramangwana.Iri boka rinoumbwa nemakambani anopfuura 170 uye rine vashandi vangangoita 20,000 munyika 20 / matunhu pasi rose.Mugore rezvemari rinopera Kurume 31, 2021, Teijin akazivisa kutengesa kwakabatanidzwa kwe836.5 bhiriyoni yen ($7.7 bhiriyoni) uye hupfumi hwese hwe1.036.4 bhiriyoni yen ($9.5 bhiriyoni).
Nguva yekutumira: Sep-10-2021